Rabies Virus Structure

14 12 is bullet shaped 180 x 75 nm in size with one end rounded or conical and the other plane or concave. The rabies virus belongs to a family known as rhabdoviridae.

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Rabies lyssavirus like many rhabdoviruses has an extremely wide host range in the wild it has been found infecting many mammalian species while in the laboratory it.

Rabies virus structure. Viral structure and replication. The rabies virus first infects a nerve cell near the site of the bite and then spreads from nerve to nerve until it reaches the spinal cord and then the brain. The rabies virus measures about 60 by 180nm in size and helical in symmetry and has the shape of a bullet with spikes on the surface of the envelope.

Spikes are made up of g protein that haem agglutinate rbcs. Rabies lyssavirus formerly rabies virus rabv is a neurotropic virus that causes rabies in humans and animals. These viruses are bullet shaped as can be seen in the electron micrograph image below.

The genome that occurs in the central core is un segmented linear negative sense 10 12 kilobase single stranded rna enclosed within a helically wound nucleocapsid. Rhabdo viruses have a unique bullet shaped appearance measuring about 180 75 nm. These spike like structures contain glycoproteins which cause the body to produce antibodies that help to neutralize the hemagglutination caused by the rabies virus.

Morphology of rabies virus. The genetic information of this virus is found as a ribo nucleo protein complex package in which the ribo nucleic acid is bound tightly by the nucleo protein that are viral in nature. Structure of rabies virus the virus is enveloped rod shaped particles measuring 75 180 nm.

The rna genome of lyssaviruses is 12 kilobases long non segmented and of negative polarity encoding five viral proteins 3 to 5. Nucleoprotein n phosphoprotein p matrix protein m glycoprotein g and polymerase l. They have an envelope with prominent spikes on surface but not very variable in appearance.

In this article we will discuss about the structure of rabies viruses explained with diagram. What is the structure of rabies virus the virus of rabies are found enveloped and have a negatively sensed single standard ribo neuclic acid genome. Mature virion appears either as bullet shaped particles with one rounded and one flattened end or as bacilliform particles.

Rabies transmission can occur through the saliva of animals and less commonly through contact with human saliva. Rabies virus is rod or bullet shaped 75 x 180 nm. The time it takes for the virus to reach the brain is known as the incubation period.

Virus envelope contains glycosylated g protein spikes embedded in lipid membrane derived from the host cell. The bullet shaped lyssavirus particle has 100 300 nm in length and 75 nm in diameter. One end conical other planar concave.

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